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Uveitis

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  • MUST Research Group

MUST Research Group

The MUST trial is a randomized controlled clinical trial comparing two treatments for patients with vision-threatening non-infectious intermediate uveitis, posterior uveitis, or panuveitis: local therapy with fluocinolone acetonide intraocular implant in affected eyes; versus standard therapy: systemic corticosteroid therapy supplemented, when indicated, by corticosteroid-sparing potent immunomodulator therapy. 


Between 2011 (the first year a MUST paper was published) and 2017, the American Uveitis Society selected 76 papers as the top papers of the year for training purposes. The MUST Trial and Follow-up Study have contributed 14 of these papers (18.4%).  

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MUST Trial PUBLICATIONS

The following journal articles may be downloaded for free.
The multicenter uveitis steroid treatment trial: rationale, design, and baseline characteristicsMorphologic assessment for glaucoma in the Multicenter Uveitis Steroid Treatment (MUST) trialRandomized comparison of systemic anti-inflammatory therapy versus fluocinolone acetonide implant for intermediate, posterior, and panuveitisIdentifying a clinically meaningful threshold for change in uveitic macular edema evaluated by optical coherence tomographyChallenges in the design and implementation of the Multicenter Uveitis Steroid Treatment (MUST) Trial--lessons for comparative effectiveness trialsHypotony in patients with uveitis: The Multicenter Uveitis Steroid Treatment (MUST) TrialAssociations among visual acuity and vision- and health-related quality of life among patients in the multicenter uveitis steroid treatment trialThe impact of macular edema on visual function in intermediate, posterior, and panuveitisOptical coherence tomography evaluation in the Multicenter Uveitis Steroid Treatment (MUST) trialRisk of elevated intraocular pressure and glaucoma in patients with uveitis: results of the multicenter uveitis steroid treatment trialFluorescein angiography versus optical coherence tomography for diagnosis of uveitic macular edemaValidation of a photographic vitreous haze grading technique for clinical trials in uveitisFundus image diagnostic agreement in uveitis utilizing free and open source softwareCost-effectiveness of fluocinolone acetonide implant versus systemic therapy for noninfectious intermediate, posterior, and panuveitisQuality of Life and Risks Associated with Systemic Anti-inflammatory Therapy versus Fluocinolone Acetonide Intraocular Implant for Intermediate Uveitis, Posterior Uveitis, or Panuveitis: Fifty-four-Month Results of the MUST Follow-up StudyFactors Predicting Visual Acuity Outcome in Intermediate, Posterior, and Panuveitis: The Multicenter Uveitis Steroid Treatment (MUST) TrialBenefits of Systemic Anti-inflammatory Therapy versus Fluocinolone Acetonide Intraocular Implant for Intermediate Uveitis, Posterior Uveitis, and Panuveitis: Fifty-four-Month Results of the Multicenter Uveitis Steroid Treatment (MUST) Trial and Follow-up StudyCataract Surgery Outcomes in Uveitis: The Multicenter Uveitis Steroid Treatment TrialMorphological assessment of the retina in uveitisAssociation Between Long-Lasting Intravitreous Fluocinolone Acetonide Implant vs Systemic Anti-inflammatory Therapy and Visual Acuity at 7 Years Among Patients With Intermediate, Posterior, or PanuveitisLongitudinal Vision-Related Quality of Life for Patients with Noninfectious Uveitis Treated with Fluocinolone Acetonide Implant or Systemic Corticosteroid TherapyIncidence and Outcome of Uveitic Glaucoma in Eyes With Intermediate, Posterior, or Panuveitis Followed up to 10 Years After Randomization to Fluocinolone Acetonide Implant or Systemic TherapySeven-Year Outcomes of Uveitic Macular Edema: The Multicenter Uveitis Steroid Treatment Trial and Follow-up Study ResultsCataract Surgery in Patients With Uveitis Treated With Systemic Therapy in the Multicenter Uveitis Steroid Treatment (MUST) Trial and Follow-up Study: Risk Factors and Outcomes

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